Fig. 8

The levels of intracellular metabolites measured by LC–MS analysis. Relative levels of intracellular metabolites in central metabolic pathways were measured by LC–MS. The levels of TA2463 at 9 h were set to 1. Each graph shows intracellular metabolite levels of TA3130, TA3130_9 h, and TA2463. The horizontal axes indicate the time of sampling and the longitudinal axes indicate the relative levels of intracellular metabolite concentration. Error bars represent the standard deviation (n = 3). White bars TA3130 without IPTG, Black bars TA3130_9 h, Gray bars TA2463. Metabolite abbreviations: G6P glucose 6-phosphate, F6P fructose 6-phosphate, F16P fructose 1,6-bisphosphate, DHAP dihydroxyacetone phosphate, GAP glyceraldehyde 3-phosphate, 2PG 2-phosphoglycerate, PEP phosphoenolpyruvate, PYR pyruvate, AcCoA acetyl-CoA, AKG α-ketoglutaric acid, OXA oxaloacetate