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Fig. 2 | Microbial Cell Factories

Fig. 2

From: Designed biosynthesis of 25-methyl and 25-ethyl ivermectin with enhanced insecticidal activity by domain swap of avermectin polyketide synthase

Fig. 2

Predicted products of engineered avermectin PKS. a AVE A1 of avermectin PKS. b AveDH2-KR2 in module 2 of avermectin PKS was replaced with MilDH2-ER2-KR2 of milbemycin PKS. c AveDH2-KR2 in module 2 and loading module AveLAT-ACP of avermectin PKS were replaced with MilDH2-ER2-KR2 of and loading module MilLAT-ACP of milbemycin PKS, respectively

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