Fig. 4
From: Optimization of yeast-based production of medicinal protoberberine alkaloids
Pilot scale fermentation of engineered S. cerevisiae strain CSY1025. a Pilot scale batch and b fed-batch 0.2-L fermentations in bioreactor with YNB-DO (2 % dextrose) with 1 mM rac-norlaudanosoline. Canadine and berberine titers were determined by LC–MS/MS from sample supernatant at indicated time points. Error bars represent the range of two independent fermentations