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Table 2 Top10 of the genes differently expressed in S. cerevisiae in single-culture (Sc) and mixed-culture (Mc) fermentations, at the three fermentation stages (24, 48 and 96 h)

From: Genomic expression program of Saccharomyces cerevisiae along a mixed-culture wine fermentation with Hanseniaspora guilliermondii

ORF Gene Function Fold change Sc/Mc
24 h
 YCL025C AGP1 Low-affinity amino acid permease with broad substrate range 13.4
 YDR508C GNP1 High-affinity glutamine permease 8.1
 YOL086 W-A   Molecular function unknown 5.7
 YHR021 W-A ECM12 Putative protein of unknown function 5.3
 YKL183C-A   Putative protein of unknown function 5.1
 YOR348C PUT4 Proline permease 4.8
 YDR130C FIN1 Spindle pole body-related intermediate filament protein 4.6
 YBL042C FUI1 High affinity uridine permease 4.5
 YAL037C-A   Putative protein of unknown function  4.4
 YBL052C SAS3 Histone acetyltransferase activity 4.0
 YHR044C DOG1 2-deoxyglucose-6-phosphate phosphatase −11.8
 YDR018C   Transferase activity, transferring acyl groups −8.9
 YPL258C THI21 Hydroxymethylpyrimidine (HMP) and HMP-phosphate kinase; involved in thiamine biosynthesis −7.9
 YDL021 W GPM2 Molecular function unknown −7.1
 YHR043C DOG2 2-deoxyglucose-6-phosphate phosphatase −6.7
 YCR020C PET18 Protein of unknown function −6.1
YLR176C RFX1 Major transcriptional repressor of DNA-damage-regulated genes −6.1
 YHL048C-A   Putative protein of unknown function −5.9
 YOL055C THI20 Trifunctional enzyme of thiamine biosynthesis, degradation and salvage −5.6
 YHR076 W PTC7 Type 2C serine/threonine protein phosphatase (PP2C) −5.5
48 h
 YLR142 W PUT1 Proline oxidase involved in utilization of proline as sole nitrogen source 55.3
 YJR152 W DAL5 Allantoate permease 52.7
 YKR039 W GAP1 General amino acid permease 25.3
 YMR107 W SPG4 Molecular function unknown 23.3
 YMR175 W SIP18 Phospholipid binding 21.2
 YMR118C   Putative mitochondrial inner membrane protein of unknown function 20.3
 YPR194C OPT2 Oligopeptide transporter 18.3
 YCR098C GIT1 Plasma membrane permease; mediates uptake of glycerophosphoinositol and glycerophosphocholine as sources of the nutrients inositol and phosphate 17.4
 YHL016C DUR3 Plasma membrane transporter for both urea and polyamines 15.4
 YCL064C CHA1 Catabolic l-serine (l-threonine) deaminase 13.8
 YMR095C SNO1 Protein of unconfirmed function; involved in pyridoxine metabolism; expression is induced during stationary phase −14.2
 YCL026C-A FRM2 Type II nitroreductase, using NADH as reductant −13.7
 YGL117 W   Putative protein of unknown function −12.9
 YBR092C PHO3 Acid phosphatase activity −10.1
 YMR094 W CTF13 Subunit of the CBF3 complex −9.9
 YML116 W ATR1 Multidrug efflux pump of the major facilitator superfamily −8.2
 YML123C PHO84 High-affinity inorganic phosphate (Pi) transporter −8.0
 YLR372 W SUR4 Elongase; involved in fatty acid and sphingolipid biosynthesis −7.8
 YGL162 W SUT1 Transcription factor of the Zn(II)2Cys6 family; positively regulates genes involved in sterol uptake under anaerobic conditions −7.2
 YBR249C ARO4 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase −6.9
96 h
 YEL061C CIN8 Kinesin motor protein 86.2
 YJL051 W IRC8 Bud tip localized protein of unknown function 43.0
 YJL148 W RPA34 RNA polymerase I subunit A34.5 28.6
 YNL129 W NRK1 Nicotinamide riboside kinase 27.6
 YLR265C NEJ1 Protein involved in regulation of non homologous end joining 25.9
 YOR177C MPC54 Component of the meiotic outer plaque 21.9
 YOR305 W RRG7 Protein of unknown function 21.0
 YLR151C PCD1 8-oxo-dGTP diphosphatase 21.0
 YKL011C CCE1 Mitochondrial cruciform cutting endonuclease 21.0
 YDR523C SPS1 Putative protein serine/threonine kinase 19.5
 YBR194 W AIM4 Protein proposed to be associated with the nuclear pore complex −4.5
 YOR090C PTC5 Mitochondrial type 2C protein phosphatase (PP2C) −3.6
 YGR213C RTA1 Protein involved in 7-aminocholesterol resistance −3.3
 YDR434 W GPI17 Transmembrane protein −3.2
 YBR111C YSA1 Nudix hydrolase family member with ADP-ribose pyrophosphatase activity −3.2
 YOL131 W   Putative protein of unknown function −3.2
 YER061C CEM1 Mitochondrial beta-keto-acyl synthase −3.1
 YNR058 W BIO3 7,8-diamino-pelargonic acid aminotransferase (DAPA) −3.1
 YCL032 W STE50 Adaptor protein for various signaling pathways −3.0
 YOR353C SOG2 Key component of the RAM signaling network −3.0