Fig. 4From: Functional analysis of filipin tailoring genes from Streptomyces filipinensis reveals alternative routes in filipin III biosynthesis and yields bioactive derivativesFilipin intermediates generated upon gene inactivation. a TLC analyses of 72 h culture broth extracts of S. filipinensis (4), S. filipinensis ΔfilC (2), S. filipinensis ΔfilD (3), and S. filipinensis ΔfilCD (1). b Relative proportions of the major filipin products accumulated by the different strains. FI, filipin I (compound Y); FII, filipin II (compound Z); FIII, filipin III; 1´-OHFI, 1´-hydroxyfillipin I (compound X).Back to article page