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Table 2 Point mutations in evolved E1 strains

From: Adaptive mutations in sugar metabolism restore growth on glucose in a pyruvate decarboxylase negative yeast strain

Name Description Evolved strains
Mth1 Negative regulator of the glucose-sensing signal transduction pathway A81/D I85/S A81/D
Cit1 Mitochondrial citrate synthase P176/Q M84/V H175/R
Hxt2 High-affinity glucose transporter of the major facilitator superfamily W466/* G75/R W466/*
Rpd3 Histone deacetylase, component of both the Rpd3S and Rpd3L complexes   85F/I 196A/V