TY - JOUR AU - Nielsen, J. AU - Jewett, M. C. PY - 2008 DA - 2008// TI - Impact of systems biology on metabolic engineering of Saccharomyces cerevisiae JO - FEMS Yeast Res VL - 8 UR - https://doi.org/10.1111/j.1567-1364.2007.00302.x DO - 10.1111/j.1567-1364.2007.00302.x ID - Nielsen2008 ER - TY - JOUR AU - Borodina, I. AU - Nielsen, J. PY - 2014 DA - 2014// TI - Advances in metabolic engineering of yeast Saccharomyces cerevisiae for production of chemicals JO - Biotechnol J VL - 9 UR - https://doi.org/10.1002/biot.201300445 DO - 10.1002/biot.201300445 ID - Borodina2014 ER - TY - JOUR AU - Hong, K. -. K. AU - Nielsen, J. PY - 2012 DA - 2012// TI - Metabolic engineering of Saccharomyces cerevisiae: a key cell factory platform for future biorefineries JO - Cell Mol Life Sci VL - 69 UR - https://doi.org/10.1007/s00018-012-0945-1 DO - 10.1007/s00018-012-0945-1 ID - Hong2012 ER - TY - JOUR AU - Li, M. AU - Borodina, I. PY - 2015 DA - 2015// TI - Application of synthetic biology for production of chemicals in yeast Saccharomyces cerevisiae JO - FEMS Yeast Res VL - 15 UR - https://doi.org/10.1093/femsyr/fou003 DO - 10.1093/femsyr/fou003 ID - Li2015 ER - TY - JOUR AU - Tippmann, S. AU - Chen, Y. AU - Siewers, V. AU - Nielsen, J. PY - 2013 DA - 2013// TI - From flavors and pharmaceuticals to advanced biofuels: production of isoprenoids in Saccharomyces cerevisiae JO - Biotechnol J VL - 8 UR - https://doi.org/10.1002/biot.201300028 DO - 10.1002/biot.201300028 ID - Tippmann2013 ER - TY - JOUR AU - Krivoruchko, A. AU - Siewers, V. AU - Nielsen, J. PY - 2011 DA - 2011// TI - Opportunities for yeast metabolic engineering: lessons from synthetic biology JO - Biotechnol J VL - 6 UR - https://doi.org/10.1002/biot.201000308 DO - 10.1002/biot.201000308 ID - Krivoruchko2011 ER - TY - JOUR AU - Jensen, M. K. AU - Keasling, J. D. PY - 2015 DA - 2015// TI - Recent applications of synthetic biology tools for yeast metabolic engineering JO - FEMS Yeast Res VL - 15 UR - https://doi.org/10.1093/femsyr/fou003 DO - 10.1093/femsyr/fou003 ID - Jensen2015 ER - TY - JOUR AU - Mora-Pale, M. AU - Sanchez-Rodriguez, S. P. AU - Linhardt, R. J. AU - Dordick, J. S. AU - Koffas, M. A. G. PY - 2014 DA - 2014// TI - Biochemical strategies for enhancing the in vivo production of natural products with pharmaceutical potential JO - Curr Opin Biotechnol VL - 25 UR - https://doi.org/10.1016/j.copbio.2013.09.009 DO - 10.1016/j.copbio.2013.09.009 ID - Mora-Pale2014 ER - TY - JOUR AU - David, F. AU - Siewers, V. PY - 2015 DA - 2015// TI - Advances in yeast genome engineering JO - FEMS Yeast Res VL - 15 UR - https://doi.org/10.1093/femsyr/fou003 DO - 10.1093/femsyr/fou003 ID - David2015 ER - TY - JOUR AU - Silva, N. A. AU - Srikrishnan, S. PY - 2012 DA - 2012// TI - Introduction and expression of genes for metabolic engineering applications in Saccharomyces cerevisiae JO - FEMS Yeast Res VL - 12 UR - https://doi.org/10.1111/j.1567-1364.2011.00769.x DO - 10.1111/j.1567-1364.2011.00769.x ID - Silva2012 ER - TY - JOUR AU - Futcher, B. AU - Carbon, J. PY - 1986 DA - 1986// TI - Toxic effects of excess cloned centromeres JO - Mol Cell Biol VL - 6 UR - https://doi.org/10.1128/MCB.6.6.2213 DO - 10.1128/MCB.6.6.2213 ID - Futcher1986 ER - TY - JOUR AU - Jensen, N. B. AU - Strucko, T. AU - Kildegaard, K. R. AU - David, F. AU - Maury, J. AU - Mortensen, U. H. PY - 2014 DA - 2014// TI - EasyClone: method for iterative chromosomal integration of multiple genes in Saccharomyces cerevisiae JO - FEMS Yeast Res VL - 14 UR - https://doi.org/10.1111/1567-1364.12118 DO - 10.1111/1567-1364.12118 ID - Jensen2014 ER - TY - JOUR AU - Johansson, B. AU - Hahn-Hägerdal, B. PY - 2002 DA - 2002// TI - Overproduction of pentose phosphate pathway enzymes using a new CRE-loxP expression vector for repeated genomic integration in Saccharomyces cerevisiae JO - Yeast VL - 19 UR - https://doi.org/10.1002/yea.833 DO - 10.1002/yea.833 ID - Johansson2002 ER - TY - JOUR AU - Radhakrishnan, P. AU - Srivastava, V. PY - 2005 DA - 2005// TI - Utility of the FLP-FRT recombination system for genetic manipulation of rice JO - Plant Cell Rep VL - 23 UR - https://doi.org/10.1007/s00299-004-0876-x DO - 10.1007/s00299-004-0876-x ID - Radhakrishnan2005 ER - TY - JOUR AU - Mikkelsen, M. D. AU - Buron, L. D. AU - Salomonsen, B. AU - Olsen, C. E. AU - Hansen, B. G. AU - Mortensen, U. H. PY - 2012 DA - 2012// TI - Microbial production of indolylglucosinolate through engineering of a multi-gene pathway in a versatile yeast expression platform JO - Metab Eng VL - 14 UR - https://doi.org/10.1016/j.ymben.2012.01.006 DO - 10.1016/j.ymben.2012.01.006 ID - Mikkelsen2012 ER - TY - JOUR AU - Jiang, W. AU - Bikard, D. AU - Cox, D. AU - Zhang, F. AU - Marraffini, L. A. PY - 2013 DA - 2013// TI - RNA-guided editing of bacterial genomes using CRISPR-Cas systems JO - Nat Biotechnol VL - 31 UR - https://doi.org/10.1038/nbt.2508 DO - 10.1038/nbt.2508 ID - Jiang2013 ER - TY - JOUR AU - Wang, H. AU - Yang, H. AU - Shivalila, C. S. AU - Dawlaty, M. M. AU - Cheng, A. W. AU - Zhang, F. PY - 2013 DA - 2013// TI - One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering JO - Cell VL - 153 UR - https://doi.org/10.1016/j.cell.2013.04.025 DO - 10.1016/j.cell.2013.04.025 ID - Wang2013 ER - TY - JOUR AU - Jiang, W. AU - Zhou, H. AU - Bi, H. AU - Fromm, M. AU - Yang, B. AU - Weeks, D. P. PY - 2013 DA - 2013// TI - Demonstration of CRISPR/Cas9/sgRNA-mediated targeted gene modification in Arabidopsis, tobacco, sorghum and rice JO - Nucleic Acids Res VL - 41 UR - https://doi.org/10.1093/nar/gkt780 DO - 10.1093/nar/gkt780 ID - Jiang2013 ER - TY - JOUR AU - Bassett, A. R. AU - Tibbit, C. AU - Ponting, C. P. AU - Liu, J. -. L. PY - 2013 DA - 2013// TI - Highly efficient targeted mutagenesis of Drosophila with the CRISPR/Cas9 system JO - Cell Rep VL - 4 UR - https://doi.org/10.1016/j.celrep.2013.06.020 DO - 10.1016/j.celrep.2013.06.020 ID - Bassett2013 ER - TY - JOUR AU - Chang, N. AU - Sun, C. AU - Gao, L. AU - Zhu, D. AU - Xu, X. AU - Zhu, X. PY - 2013 DA - 2013// TI - Genome editing with RNA-guided Cas9 nuclease in zebrafish embryos JO - Cell Res VL - 23 UR - https://doi.org/10.1038/cr.2013.45 DO - 10.1038/cr.2013.45 ID - Chang2013 ER - TY - JOUR AU - Mali, P. AU - Yang, L. AU - Esvelt, K. M. AU - Aach, J. AU - Guell, M. AU - DiCarlo, J. E. PY - 2013 DA - 2013// TI - RNA-guided human genome engineering via Cas9 JO - Science VL - 339 UR - https://doi.org/10.1126/science.1232033 DO - 10.1126/science.1232033 ID - Mali2013 ER - TY - JOUR AU - Cong, L. AU - Ran, F. A. AU - Cox, D. AU - Lin, S. AU - Barretto, R. AU - Habib, N. PY - 2013 DA - 2013// TI - Multiplex genome engineering using CRISPR/Cas systems JO - Science VL - 339 UR - https://doi.org/10.1126/science.1231143 DO - 10.1126/science.1231143 ID - Cong2013 ER - TY - JOUR AU - Ronda, C. AU - Pedersen, L. E. AU - Hansen, H. G. AU - Kallehauge, T. B. AU - Betenbaugh, M. J. AU - Nielsen, A. T. PY - 2014 DA - 2014// TI - Accelerating genome editing in CHO cells using CRISPR Cas9 and CRISPy, a web-based target finding tool JO - Biotechnol Bioeng VL - 111 UR - https://doi.org/10.1002/bit.25233 DO - 10.1002/bit.25233 ID - Ronda2014 ER - TY - JOUR AU - DiCarlo, J. E. AU - Norville, J. E. AU - Mali, P. AU - Rios, X. AU - Aach, J. AU - Church, G. M. PY - 2013 DA - 2013// TI - Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems JO - Nucleic Acids Res VL - 41 UR - https://doi.org/10.1093/nar/gkt135 DO - 10.1093/nar/gkt135 ID - DiCarlo2013 ER - TY - JOUR AU - Bao, Z. AU - Xiao, H. AU - Liang, J. AU - Zhang, L. AU - Xiong, X. AU - Sun, N. PY - 2014 DA - 2014// TI - Homology-integrated CRISPR-Cas (HI-CRISPR) system for one-step multigene disruption in Saccharomyces cerevisiae JO - ACS Synth Biol VL - 4 UR - https://doi.org/10.1021/sb500255k DO - 10.1021/sb500255k ID - Bao2014 ER - TY - JOUR AU - Ryan, O. W. AU - Skerker, J. M. AU - Maurer, M. J. AU - Li, X. AU - Tsai, J. C. AU - Poddar, S. PY - 2014 DA - 2014// TI - Selection of chromosomal DNA libraries using a multiplex CRISPR system JO - Elife ID - Ryan2014 ER - TY - JOUR AU - Jakočiūnas, T. AU - Bonde, I. AU - Herrgård, M. AU - Harrison, S. J. AU - Kristensen, M. AU - Pedersen, L. E. PY - 2015 DA - 2015// TI - Multiplex metabolic pathway engineering using CRISPR/Cas9 in Saccharomyces cerevisiae JO - Metab Eng VL - 28 UR - https://doi.org/10.1016/j.ymben.2015.01.008 DO - 10.1016/j.ymben.2015.01.008 ID - Jakočiūnas2015 ER - TY - STD TI - Mans R, van Rossum HM, Wijsman M, Backx A, Kuijpers NGA, van den Broek M et al (2015) CRISPR/Cas9: a molecular Swiss army knife for simultaneous introduction of multiple genetic modifications in Saccharomyces cerevisiae. FEMS Yeast Res 15:fov004–fov004 ID - ref28 ER - TY - JOUR AU - Stovicek, V. AU - Borodina, I. AU - Forster, J. PY - 2015 DA - 2015// TI - CRISPR-Cas system enables fast and simple genome editing of industrial Saccharomyces cerevisiae strains JO - Metab Eng Commun VL - 2 UR - https://doi.org/10.1016/j.meteno.2015.03.001 DO - 10.1016/j.meteno.2015.03.001 ID - Stovicek2015 ER - TY - JOUR AU - Storici, F. AU - Durham, C. L. AU - Gordenin, D. A. AU - Resnick, M. A. PY - 2003 DA - 2003// TI - Chromosomal site-specific double-strand breaks are efficiently targeted for repair by oligonucleotides in yeast JO - Proc Natl Acad Sci VL - 100 UR - https://doi.org/10.1073/pnas.2036296100 DO - 10.1073/pnas.2036296100 ID - Storici2003 ER - TY - JOUR AU - Kuijpers, N. G. A. AU - Solis-Escalante, D. AU - Bosman, L. AU - Broek, M. AU - Pronk, J. T. AU - Daran, J. -. M. PY - 2013 DA - 2013// TI - A versatile, efficient strategy for assembly of multi-fragment expression vectors in Saccharomyces cerevisiae using 60 bp synthetic recombination sequences JO - Microb Cell Fact VL - 12 UR - https://doi.org/10.1186/1475-2859-12-47 DO - 10.1186/1475-2859-12-47 ID - Kuijpers2013 ER - TY - JOUR AU - Horwitz, A. A. AU - Walter, J. M. AU - Schubert, M. G. AU - Kung, S. H. PY - 2015 DA - 2015// TI - Efficient multiplexed integration of synergistic alleles and metabolic pathways in yeasts via CRISPR-Cas JO - Cell Syst VL - 1 UR - https://doi.org/10.1016/j.cels.2015.07.009 DO - 10.1016/j.cels.2015.07.009 ID - Horwitz2015 ER - TY - JOUR AU - Donald, K. A. AU - Hampton, R. Y. AU - Fritz, I. B. PY - 1997 DA - 1997// TI - Effects of overproduction of the catalytic domain of 3-hydroxy-3-methylglutaryl coenzyme A reductase on squalene synthesis in Saccharomyces cerevisiae JO - Appl Environ Microbiol VL - 63 ID - Donald1997 ER - TY - JOUR AU - Yan, G. -. L. AU - Wen, K. -. R. AU - Duan, C. -. Q. PY - 2012 DA - 2012// TI - Enhancement of β-carotene production by over-expression of HMG-CoA reductase coupled with addition of ergosterol biosynthesis inhibitors in recombinant Saccharomyces cerevisiae JO - Curr Microbiol VL - 64 UR - https://doi.org/10.1007/s00284-011-0044-9 DO - 10.1007/s00284-011-0044-9 ID - Yan2012 ER - TY - JOUR AU - Verwaal, R. AU - Wang, J. AU - Meijnen, J. -. P. AU - Visser, H. AU - Sandmann, G. AU - Berg, J. A. PY - 2007 DA - 2007// TI - High-level production of beta-carotene in Saccharomyces cerevisiae by successive transformation with carotenogenic genes from Xanthophyllomyces dendrorhous JO - Appl Environ Microbiol VL - 73 UR - https://doi.org/10.1128/AEM.02759-06 DO - 10.1128/AEM.02759-06 ID - Verwaal2007 ER - TY - JOUR AU - Yamano, S. AU - Ishii, T. AU - Nakagawa, M. AU - Ikenaga, H. AU - Misawa, N. PY - 1994 DA - 1994// TI - Metabolic engineering for production of beta-carotene and lycopene in Saccharomyces cerevisiae JO - Biosci Biotechnol Biochem VL - 58 UR - https://doi.org/10.1271/bbb.58.1112 DO - 10.1271/bbb.58.1112 ID - Yamano1994 ER - TY - JOUR AU - Janbandhu, V. C. AU - Moik, D. AU - Fässler, R. PY - 2014 DA - 2014// TI - Cre recombinase induces DNA damage and tetraploidy in the absence of loxP sites JO - Cell Cycle VL - 13 UR - https://doi.org/10.4161/cc.27271 DO - 10.4161/cc.27271 ID - Janbandhu2014 ER - TY - JOUR AU - Heider, S. A. E. AU - Peters-Wendisch, P. AU - Wendisch, V. F. AU - Beekwilder, J. AU - Brautaset, T. PY - 2014 DA - 2014// TI - Metabolic engineering for the microbial production of carotenoids and related products with a focus on the rare C50 carotenoids JO - Appl Microbiol Biotechnol VL - 98 UR - https://doi.org/10.1007/s00253-014-5693-8 DO - 10.1007/s00253-014-5693-8 ID - Heider2014 ER - TY - JOUR AU - Vachali, P. AU - Bhosale, P. AU - Bernstein, P. S. PY - 2012 DA - 2012// TI - Microbial carotenoids JO - Methods Mol Biol VL - 898 UR - https://doi.org/10.1007/978-1-61779-918-1_2 DO - 10.1007/978-1-61779-918-1_2 ID - Vachali2012 ER - TY - JOUR AU - Sandmann, G. PY - 1994 DA - 1994// TI - Carotenoid biosynthesis in microorganisms and plants JO - Eur J Biochem VL - 223 UR - https://doi.org/10.1111/j.1432-1033.1994.tb18961.x DO - 10.1111/j.1432-1033.1994.tb18961.x ID - Sandmann1994 ER - TY - JOUR AU - Lee, P. C. AU - Schmidt-Dannert, C. PY - 2002 DA - 2002// TI - Metabolic engineering towards biotechnological production of carotenoids in microorganisms JO - Appl Microbiol Biotechnol VL - 60 UR - https://doi.org/10.1007/s00253-002-1101-x DO - 10.1007/s00253-002-1101-x ID - Lee2002 ER - TY - JOUR AU - Ye, V. M. AU - Bhatia, S. K. PY - 2012 DA - 2012// TI - Pathway engineering strategies for production of beneficial carotenoids in microbial hosts JO - Biotechnol Lett VL - 34 UR - https://doi.org/10.1007/s10529-012-0921-8 DO - 10.1007/s10529-012-0921-8 ID - Ye2012 ER - TY - JOUR AU - Kennedy, M. A. AU - Bard, M. PY - 2001 DA - 2001// TI - Positive and negative regulation of squalene synthase (ERG9), an ergosterol biosynthetic gene, in Saccharomyces cerevisiae JO - Biochim Biophys Acta VL - 1517 UR - https://doi.org/10.1016/S0167-4781(00)00246-3 DO - 10.1016/S0167-4781(00)00246-3 ID - Kennedy2001 ER - TY - JOUR AU - Sherman, F. PY - 2002 DA - 2002// TI - Getting started with yeast JO - Meth Enzymol VL - 350 UR - https://doi.org/10.1016/S0076-6879(02)50954-X DO - 10.1016/S0076-6879(02)50954-X ID - Sherman2002 ER - TY - JOUR AU - Gietz, R. D. AU - Schiestl, R. H. PY - 2007 DA - 2007// TI - High-efficiency yeast transformation using the LiAc/SS carrier DNA/PEG method JO - Nat Protoc VL - 2 UR - https://doi.org/10.1038/nprot.2007.13 DO - 10.1038/nprot.2007.13 ID - Gietz2007 ER -