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Fig. 5 | Microbial Cell Factories

Fig. 5

From: Broadly protective immunity against divergent influenza viruses by oral co-administration of Lactococcus lactis expressing nucleoprotein adjuvanted with cholera toxin B subunit in mice

Fig. 5

Percent survival. Two weeks after the last immunization, mice were intranasally infected with 20 µL of 104 EID50 of lethal dose of A/California/04/2009(H1N1) (a), A/Guangdong/08/95 (H3N2) (b) or A/chicken/Henan/12/2004 (H5N1) (c). For a parallel experiment, L. lactis/pNZ8110-pgsA-HA1 alone or adjuvanted with CTB was used as a control for virus challenge. 10 mice/group were used to record survival rate.

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Microbial Cell Factories

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