Skip to main content
Fig. 4 | Microbial Cell Factories

Fig. 4

From: Broadly protective immunity against divergent influenza viruses by oral co-administration of Lactococcus lactis expressing nucleoprotein adjuvanted with cholera toxin B subunit in mice

Fig. 4

Cross-protection against divergent influenza A viruses. The results are expressed in terms of percent body weight (a–c) and lung viral titers (d–f). For a parallel experiment, L. lactis/pNZ8110-pgsA-HA1 alone or adjuvanted with CTB was used as a control for virus challenge. Data for lung viral titers (n = 3 mice/group) are represented as mean ± SD. Asterisk indicates significant difference compared with PBS, L. lactis/pNZ8008, L. lactis/pNZ8008+CTB, L. lactis/pNZ8008-NP or L. lactis/pNZ8110-pgsA-HA1 controls (p <  0.05).

Back to article page

Microbial Cell Factories

ISSN: 1475-2859

Contact us