Inhibition of pathogenic and spoilage bacteria by a novel biofilm-forming Lactobacillus isolate: a potential host for the expression of heterologous proteins

Table 1 Antibiotic susceptibility of Lb. plantarum PA21 analysed using agar-disc diffusion method

Antibiotic	Concentration	Target	Diameter of inhibition zone of strains (mm) Lb. plantarum PA21/Lb. plantarum ATCC 14917
Aminoglycoside		Ribosome
Kanamycin	30 μg		–	–
Streptomycin	10 μg		–	–
Penicillin/β-lactam		Cell wall
Penicillin G	10 units		20	15
Macrolide		Ribosome
Erythromycin	15 μg		18	22
Polymyxins		Cell membrane
Bacitracin	10 units		14	14
Phenicole		Ribosome
Chloramphenicol	30 μg		17	20
Quinolone		DNA topoisomerase
Nalidixic acid	30 μg		–	–
Tetracycline		Ribosome
Tetracycline	30 μg		15	15
Glycopeptides		Cell wall
Vancomycin	30 μg		–	–
Lincosamides		Ribosome
Clindamycin	10 μg		11	18

Susceptibilities were evaluated by measuring (in mm) zones of growth inhibition in standard disc diffusion assay. Lb. plantarum PA21 is resistant to kanamycin, streptomycin, nalidixic acid and vancomycin.

ISSN: 1475-2859