Table 1 Central composite design matrix used to study the influence of reactional temperature (°C) and pH on lipase activity (U mL⁻¹) and the respective observed (y) and fitted (\( \hat{y} \)) values and residual errors (ε)

6.5

2.44

2.17

0.271

6.5

2.48

2.17

0.319

6.5

2.32

2.17

0.151

9.5

0.88

1.08

−0.200

9.5

0.88

1.08

−0.196

9.5

0.86

1.08

−0.219

8

2.09

1.94

0.147

8

1.90

1.94

−0.042

8

1.88

1.94

−0.056

8

1.93

1.94

−0.006

8

1.90

1.94

−0.042

8

0.48

0.39

0.080

8

0.49

0.39

0.091

8

2.15

2.17

−0.015

8

2.14

2.17

−0.031

6.94

2.30

2.46

−0.161

6.94

2.31

2.46

−0.155

6.94

2.41

2.46

−0.052

9.06

1.75

1.70

0.054

9.06

1.78

1.70

0.079

9.06

1.96

1.70

0.262

6.94

0.89

1.21

−0.324

6.94

0.82

1.21

−0.393

9.06

0.65

0.45

0.200

9.06

0.68

0.45

0.236