Figure 3
From: Human FMO2-based microbial whole-cell catalysts for drug metabolite synthesis
FMO2 based biotransformations of ethionamide. a Whole-cell conversions of ethionamide employing E. coli catalysts based on FMO2*1 and truncations thereof. The conversions were conducted with whole cells corresponding to 15 OD600 units and 1 mM ethionamide for 16 h. Values are shown as mean ± SD of measurements performed in triplicates. Cells carrying the empty vector served as negative control (pMS470). b Reaction scheme of the FMO2 catalyzed ethionamide oxidation according to the literature [8, 9].