Fig. 4
From: Metabolic engineering of a tyrosine-overproducing yeast platform using targeted metabolomics
An overview of an in silico strain design for growth-coupled tyrosine production. Metabolic fluxes for wild-type a and mutant b strains were predicted by maximizing biomass production using the iMM904 model during respiratory growth on glucose. Knockouts obtained using the GDLS strain design algorithm are shown in red font. The flux distributions are visualized using Omix Visualization software [54], and arrow width correlates to predicted flux. Reaction edges carrying no flux are shaded grey