Fig. 2
From: Metabolic engineering of a tyrosine-overproducing yeast platform using targeted metabolomics
Targeted metabolite analysis of S. cerevisiae strains used in this study. Complete phenotypic descriptions of the strains are given in Table 1. Metabolite levels are shown in specific concentrations per g DCW. Low and high ends of concentration ranges per metabolite represented by white and black, respectively. Abbreviations: PEP, phosphoenolpyruvate; E4P, erythrose 4-phosphate; DHS, dehydroshikimate; PPH/PPY, prephenate/phenylpyruvate measured as a mixed peak by HPLC-PDA; 4HPP, 4-hydroxyphenylpyruvate; 4HPAA, 4-hydroxyphenylacetaldehyde; 4HPAC, 4-hydroxyphenylacetate. Intra and extra denote intra-cellular and extra-cellular metabolites, respectively