Figure 1

Metabolic map of isobutanol biosynthesis by S. cerevisiae. The genes deleted to prevent competitive pathways are indicated by white letters on orange backgrounds (ALD6, ECM31 and ILV1). The overexpressed genes are indicated by white letters on blue backgrounds (kivd, ADH6, ILV2, PYC2, MDH2, MAE1 and sMAE1).