Figure 4From: Identification of a cluster-situated activator of oxytetracycline biosynthesis and manipulation of its expression for improved oxytetracycline production in Streptomyces rimosus Overexpression of otcR improves OTC production. A. OTC production of S. rimosus M4018 and M4018::otcR in R5 and FM media. The values are means ± SD from three independent experiments. B. Activities of oxy promoters in S. rimosus M4018 and M4018::otcR reported by GFP. Green fluorescence of different strains was measured after incubation in R5 medium at stationary phase (10 d). The values are means ± SD from three independent experiments.Back to article page