Figure 2From: Identification of a cluster-situated activator of oxytetracycline biosynthesis and manipulation of its expression for improved oxytetracycline production in Streptomyces rimosus The predicted SARP-binding sites of oxy and ctc clusters. A. Organization of ctc cluster from S. aureofaciens and oxy cluster from S. rimosus. B. The predicted SARP-binding consensus sequences of ctc and oxy clusters. The dotted arrows mark the direct repeat sequences identified in this study. Putative -10 and -35 regions are underlined and indicate with bold letters. C. Analysis of the consensus SARP- binding sequences of the promoter regions from ctc and oxy using MeMe. The dotted arrows mark the direct repeat sequences. D. Analysis of the SARP- binding consensus sequences of the promoter regions from oxy. The dotted arrows mark the direct repeat sequences identified by MeMe. The conserved consensus sequence of -10 regions was underlined.Back to article page