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Figure 7 | Microbial Cell Factories

Figure 7

From: Fungal cytochrome P450 monooxygenases of Fusarium oxysporum for the synthesis of ω-hydroxy fatty acids in engineered Saccharomyces cerevisiae

Figure 7

Superimposition of docked complexes of fatty acids in the active site of FoCYP s. (A) Superimposition of docked complexes of caprylic acid (cyan stick), capric acid (blue stick), and lauric acid (green stick) in the active site of FoCYP539A7 (pink ribbons). Fatty acids show hydrogen bond interaction with Asn106 of FoCYP539A7 and the ω carbon faces towards the ferric atom of heme. (B) Superimposition of docked complexes of capric acid (blue stick), lauric acid (green stick) and myristic acid (orange sticks) in the active site of FoCYP655C2 (cyan ribbons). Fatty acids show hydrogen bond interaction with Arg235 of FoCYP539A7 and the ω carbon faces towards the ferric atom of heme except myristic acid. The oxygen and nitrogen are represented in red and blue, and heme is represented as red sticks.

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