Figure 8From: Process development for the production of 15β-hydroxycyproterone acetate using Bacillus megaterium expressing CYP106A2 as whole-cell biocatalyst Effect of different cell permeabilization methods and cofactor addition on 15β-hydroxycyproterone acetate production. White bars represent the results without cofactor addition, grey bars have 1 mM NADPH and the black bar have 2 mM NADPH added. All reactions were run using 1 mM cyproterone acetate, 2% DMSO and 100 g/L WCW cells from the same fermentation batch. Error bars are 1σ.Back to article page