Table 2 Engineered strains for diols production

1,3-Propanediol

Clostridium acetobutylicum DG1(pSPD5)

Glycerolkinase, Glycerol-3-phosphate dehydrogenase

Glycerol

Continuous cultures

-

[65]

Recombinant E. coli

Glycerol3-phosphate dehydrogenase, glycerol 3-phosphate phosphatase, Insert dhaB1-3, yqhD, Delete tpi

Glucose

Fed-batch fermentation

4 g/l/h

[8]

1,2-Propanediol

Escherichia coli

Methylglyoxalsynthase, Glycerol dehydrogenase, Aldehyde oxidoreductase, ATP-dependentdihydroxyacetone kinase

Glycerol

Multi-fermentation

0.21 g/g

[41]

Saccharomyces cerevisiae(sJDPMG)

Overexpress genes:gdh,GUP1, mgs, gldA

Glycerol

Flask cultivation

0.21 ± 0.02 g/g

[45]

Synechococcus elongates PCC 7942

mgsA, yqhD, adh

CO₂

Light condition

--

[26]

Corynebacterium glutamicum

Overexpress genes:mgs, cgR_2242

Glucose

Flask cultivation

20 mg/l/h

[38]

Pichia pastoris

Introduce genes:mgsA, yqhD, glydh

Glycerol

Fed-batch fermentation

2 mg/l/h

[70]

2,3-Butanediol

SerratiamarcescensH303

swrW

Sucrose

Fed-batch culturing

3 g/l/h

[56]

Bacillus licheniformis

Knock out theldh

Glucose/Xylose

Anaerobic fermentation

0.45 g/g (BL5 glucose), 0.44 g/g(BL8 xylose)

[51]

Escherichia coli SGSB03

Introduce genes: budA, meso-budC

Glucose/Glycerol

Batch culture

0.31 g/g (glucose)

[15]

0.21 g/g (glycerol,)

Escherichia coli MGLAP

Acetoacetate synthase, Acetoacetatedecarboxylase, Secondary alcohol dehydrogenase

Cellodextrin

Anaerobic cultivation

0.84 g/g

[19]

1,4-Butanediol

Escherichia coli

Knock out genes: adhE, pflB, ldhA, Replace lpdA

Fed-batchfermentation

0.16 g /l/h

[58]