Figure 1From: Catechol biosynthesis from glucose in Escherichia coli anthranilate-overproducer strains by heterologous expression of anthranilate 1,2-dioxygenase from Pseudomonas aeruginosa PAO1 Metabolic network related to catechol biosynthesis in E. coli . Arrows with dashed lines indicate more than one enzymatic reaction. Metabolite symbols: G6P, glucose 6-phosphate; PYR, pyruvate; PEP, phosphoenolpyruvate; E4P, erythrose 4-phosphate; DAHP, 3-deoxy-D-arabino-heptulosonate 7-phosphate; CHA, chorismate; DHS, dehydroshikimic acid; ANT, anthranilate; L-Phe, L-phenylalanine; L-Tyr, L-tyrosine; L-Trp, L-tryptophan; TCA, tricarboxylic acid cycle; PTS, phosphotransferase transport system; tktA, transketolase; aroG fbr, feedback inhibition resistant DAHP synthase; trpED, anthranilate synthase-phosphoribosyl transferase complex; AntAB, terminal oxygenase component and AntC, reductase component of anthranilate 1,2-dioxygenase.Back to article page