Table 3 Differentially expressed and annotated genes in the Δ aft1 vs. control (wild type) strain
From: Pichia pastoris Aft1 - a novel transcription factor, enhancing recombinant protein secretion
Up-regulated genes (Δaft1vs. control) | |
|---|---|
GO slim term - Biological process | Number (Genes) |
GO:0006811 ion transport | 7 ( AQR1 ATX1 GEF1 MEP2 TPO3 YHL008C ZRT1 ) |
GO:0008150 biological_process* | 6 ( ECM13 GPM3 YEL023C YLR156C-A YLR278C YOR292C ) |
GO:0055085 transmembrane transport | 6 ( AQR1 GEF1 MEP2 STL1 TPO3 ZRT1 ) |
GO:0006366 transcription from RNA polymerase II promoter | 5 ( GCR1 PHD1 RPM2 UGA3 YLR278C ) |
GO:0042221 response to chemical | 5 ( AQR1 ATX1 GCR1 SLI1 UGA3 ) |
GO:0006520 cellular amino acid metabolic process | 4 ( ADH2 ECM4 SFA1 UGA3 ) |
GO:0007124 pseudohyphal growth | 4 ( HMS1 MEP2 PHD1 PTP1 ) |
GO:0051186 cofactor metabolic process | 4 ( ADH2 ALD4 BIO2 THI21 ) |
GO:0005975 carbohydrate metabolic process | 3 ( DOG1 GCR1 GPM3 ) |
GO:0006091 generation of precursor metabolites and energy | 2 ( GCR1 GPM3 ) |
GO:0006766 vitamin metabolic process | 2 ( BIO2 THI21 ) |
GO:0006873 cellular ion homeostasis | 2 ( ATX1 GEF1 ) |
GO:0055086 nucleobase-containing small molecule metabolic process | 2 ( ADH2 ALD4 ) |
GO:0001403 invasive growth in response to glucose limitation | 1 ( PTP1 ) |
GO:0002181 cytoplasmic translation | 1 ( RPM2 ) |
GO:0006325 chromatin organization | 1 ( GCR1 ) |
GO:0006397 mRNA processing | 1 ( RPM2 ) |
GO:0006470 protein dephosphorylation | 1 ( PTP1 ) |
GO:0006629 lipid metabolic process | 1 ( YJU3 ) |
GO:0006865 amino acid transport | 1 ( AQR 1 ) |
GO:0006979 response to oxidative stress | 1 ( ATX1 ) |
GO:0007005 mitochondrion organization | 1 ( RPM2 ) |
GO:0008033 tRNA processing | 1 ( RPM2 ) |
GO:0008643 carbohydrate transport | 1 ( STL1 ) |
GO:0070647 protein modification by small protein conjugation or removal | 1 ( PCI8 ) |
Down-regulated genes (Δ aft1 vs. control) | |
GO slim term - Biological process | Number (Genes) |
GO:0006811 ion transport | 4 ( ATO2 JEN1 TAT2 VMA8 ) |
GO:0055085 transmembrane transport | 4 ( ITR1 JEN1 PEX13 TAT2 ) |
GO:0006281 DNA repair | 3 ( PCD1 RVB1 YRA1 ) |
GO:0006325 chromatin organization | 3 ( ACS1 RLF2 RVB1 ) |
GO:0006366 transcription from RNA polymerase II promoter | 3 ( MIG1 RVB1 YHP1 ) |
GO:0006974 cellular response to DNA damage stimulus | 3 ( PCD1 RVB1 YRA1 ) |
GO:0008150 biological_process* | 3 ( NBA1 TOS8 YHR177W ) |
GO:0005975 carbohydrate metabolic process | 2 ( CTS1 MIG1 ) |
GO:0006766 vitamin metabolic process | 2 ( SNO1 SNZ3 ) |
GO:0051186 cofactor metabolic process | 2 ( ACS1 SNZ3 ) |
GO:0055086 nucleobase-containing small molecule metabolic process | 2 ( PCD1 YRA1 ) |
GO:0070271 protein complex biogenesis | 2 ( PEX13 RLF2 ) |
GO:0000278 mitotic cell cycle | 1 ( YHP1 ) |
GO:0000910 cytokinesis | 1 ( CTS1 ) |
GO:0002181 cytoplasmic translation | 1 ( RPL4A ) |
GO:0006091 generation of precursor metabolites and energy | 1 ( ACS1 ) |
GO:0006520 cellular amino acid metabolic process | 1 ( SNO1 ) |
GO:0006605 protein targeting | 1 ( PEX13 ) |
GO:0006865 amino acid transport | 1 ( TAT2 ) |
GO:0006873 cellular ion homeostasis | 1 ( VMA8 ) |
GO:0007031 peroxisome organization | 1 ( PEX13 ) |
GO:0008643 carbohydrate transport | 1 ( JEN1 ) |
GO:0015931 nucleobase-containing compound transport | 1 ( YRA1 ) |
GO:0016570 histone modification | 1 ( ACS1 ) |
GO:0018193 peptidyl-amino acid modification | 1 ( ACS1 ) |
GO:0042221 response to chemical | 1 ( MIG1 ) |
GO:0042594 response to starvation | 1 ( MIG1 ) |
GO:0043543 protein acylation | 1 ( ACS1 ) |
GO:0048193 Golgi vesicle transport | 1 ( BRE5 ) |
GO:0051049 regulation of transport | 1 ( BRE5 ) |
GO:0051169 nuclear transport | 1 ( YRA1 ) |
GO:0070647 protein modification by small protein conjugation or removal | 1 ( BRE5 ) |