Figure 2From: Metabolic engineering of Escherichia coli for the production of riboflavin Performance of riboflavin biosynthesis pathway with different plasmid replication origin and gene source. Plasmid backbone p20C, p15C and p5C have pBR322, p15A and pSC101 replication origin, respectively. ribA, ribB, ribD, ribE, and ribC are genes cloned from E. coli; BSribA, BSribB, BSribD, BSribE, BSribC genes are cloned from B. subtilis. Trc, Trc promoter. Gray bars represent riboflavin titer (mg/L). Blank bars represent riboflavin yield (mg riboflavin/g-consumed glucose). Symbols represent the mean values for each parameter ± standard deviation of measurements from three independent experiments.Back to article page