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Table 1 Box-Behnken matrix representing real levels of operational parameters.

From: Development of a two-step cultivation strategy for the production of vitamin B12 by Bacillus megaterium

  Sample no. A: Step 1 + O2Hours B: Step 2 -O2Hours C: Step 3 + O2Hours
Run
1 8 18 15 18
2 14 9 15 12
3 15 9 15 12
4 1 0 6 12
5 6 18 15 6
6 11 9 6 18
7 3 0 24 12
8 5 0 15 6
9 17 9 15 12
10 13 9 15 12
11 12 9 24 18
12 10 9 24 6
13 4 18 24 12
14 9 9 6 6
15 7 0 15 18
16 16 9 15 12
17 2 18 6 12