From: Fed-batch fermentation of GM-CSF-producing glycoengineered Pichia pastoris under controlled specific growth rate
Specific growth
rate, μ (h-1)
Elapsed fermentation
time (h)
Wet cell
density (g/l)
Max mGM-CSF
yielda(mg/l)
0.0624
47.76
368.3
442.7
0.0459
67.99
448
644.0
0.0332
68.25
370.25
644.4
0.015
221.4
760.4