Table 3 Specific fluxes (fluxes normalized by the biomass yield estimate: (mmolmetablite/h)(gbiomass/h)-1) in the central metabolic pathways of the experiments listed in Table 1.
From: Metabolic response of Geobacter sulfurreducens towards electron donor/acceptor variation
pathway enzymes | specific metabolic fluxes | pathway description | |||
|---|---|---|---|---|---|
| Â | E1 | E2 | E3 | E4 | Â |
ACKr, PTAr | 369 | 166 | 65.2 | 66.3 | acetate uptake |
PFK, FBP, FBA, TPI | 1.38 | 1.38 | 1.38 | 1.38 | lower gluconeogenesis |
GAPD, PGK | 3.25 | 3.25 | 3.25 | 3.25 | Â |
PGM, ENO | 57.5 | 27.1 | 25.6 | 15.3 | upper gluconeogenesis |
PYK, PPDK, PPS | 62.6 | 28.4 | 11.1 | 1.60 | Â |
PDH, POR | 8.68 | 8.68 | -7.63 | -3.37 | pyruvate ↔ acetyl-CoA |
PEPCK, PEPCKG | -4.62 | -0.77 | 15.0 | 14.2 | gluconeogenesis initiation |
TKT1 | 0.05 | 0.05 | 0.05 | 0.05 | pentose phosphate pathway |
TAL | 0.05 | 0.05 | 0.05 | 0.05 | Â |
TKT2 | 0.31 | 0.31 | 0.31 | 0.31 | Â |
CS, ACONT | 370 | 154 | 69.3 | 66.5 | TCA cycle |
ICDHy | 370 | 154 | 69.3 | 66.5 | Â |
AKGD, OOR | 370 | 153 | 68.5 | 65.7 | Â |
FRD5 | 370 | 153 | -116 | -99.5 | Â |
FUM | 370 | 153 | 84.8 | 77.8 | Â |
MDH | 374 | 153 | 83.8 | 80.0 | Â |
decarboxylic acid transporter | / | / | 202 | 177 | fumarate uptake |
| Â | / | / | 185 | 165 | succinate secretion |