Table 2 Abbreviations and EC numbers of the enzymes considered in the central metabolic network of G. sulfurreducens for 13C metabolic flux analysis.

ACKr

2.7.2.1

acetate kinase

PTAr

2.3.1.8

phosphotransacetylase

PFK

2.7.1.11

phosphofructokinase

FBP

3.1.3.11

fructose-bisphosphatase

FBA

4.1.2.13

fructose-bisphosphate aldolase

TPI

5.3.1.1

triose-phosphate isomerase

GAPD

1.2.1.12

glyceraldehyde-3-phosphate dehydrogenase (NAD)

PGK

2.7.2.3

phosphoglycerate kinase

PGM

5.4.2.1

phosphoglycerate mutase

ENO

4.2.1.11

enolase

PYK

2.7.1.40

pyruvate kinase

PPDK

2.7.9.1

pyruvate phosphate dikinase

PPS

2.7.9.2

phosphoenolpyruvate synthase

PDH

1.2.1.51

pyruvate dehydrogenase

POR

1.2.7.1

pyruvate synthase (pyruvate ferredoxin oxidoreductase)

TKT1

2.2.1.1

transketolase

TAL

2.2.1.2

transaldolase

TKT2

2.2.1.1

transketolase

CS

4.1.3.7

citrate synthase

ACONT

4.2.1.3

aconitase

ICDHy

1.1.1.42

isocitrate dehydrogenase (NADP)

AKGD

1.2.4.2

2-oxoglutarate dehydrogenase

OOR

1.2.7.3

2-oxoglutarate synthase

SUCOAS

6.2.1.5

succinyl-CoA synthetase (ADP-forming)

ATO

2.8.3.8

acetate CoA-transferase

FRD5

1.3.5.1

succinate dehydrogenase (menaquinone 7)

FUM

4.2.1.2

fumarase

MDH

1.1.1.37

malate dehydrogenase

PC

6.4.1.1

pyruvate carboxylase

ME1

1.1.1.38

malic enzyme (NAD)

ME2

1.1.1.40

malic enzyme (NADP)

PEPCK

4.1.1.49

phosphoenolpyruvate carboxykinase

PEPCKG

4.1.1.32

phosphoenolpyruvate carboxykinase (GTP)

ASPTA1

2.6.1.1

aspartate transaminase

THRS

4.2.3.1

threonine synthase

THRD

4.3.1.19

threonine deaminase

LEUB

1.1.1.85

3-isopropylmalate dehydrogenase

THRLAD

4.1.2.5

threonine aldolase

ADA

1.2.1.10

acetaldehyde dehydrogenase

GHMT

2.1.2.1

glycine hydroxymethyltransferase

PSP

3.1.3.3

phosphoserine phosphatase

SERD

4.3.1.17

serine deaminase