Figure 2

In vivo flux estimates (95% confidence intervals given for the flux mean estimates) for the central metabolic network of G. sulfurreducens , corresponding to E1, E2, E3, and E4 (Table 1). All fluxes are normalized to acetate uptake (ACKr, PTAr). Gray double-headed arrows indicate bidirectional reactions, and the black arrowa with plus signs correspond to the net direction of a positive value for the bidirectional reactions. Unidirectional reactions were indicated by gray single-headed arrows. The subscript "ex" denotes extracellular metabolites. The abbreviations (pathway enzymes) are listed in Table 2, and precursor demand for biomass synthesis (precursors in yellow color) in Table 4.