Figure 8From: Modeling and simulation of the main metabolism in Escherichia coli and its several single-gene knockout mutants with experimental verificationEffect of Pyk knockout on the fluxes at the dilution rate of 0.2 h-1 in the continuous culture, where bold lines indicates up-regulation and dotted line show down-regulation. The upper figure for the wild type and the lower figure for the Pyk knockout mutant: (A) simulation result of Pyk knockout mutant as compared to wild type; (B) experimental result from [17].Back to article page