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Figure 1 | Microbial Cell Factories

Figure 1

From: Molecular cloning and biochemical characterization of a novel erythrose reductase from Candida magnoliae JH110

Figure 1

Multiple alignment of the deduced amino acid sequence for the ER gene from C. magnoliae JH110 with other AKRs showing erythrose reduction activity. AKRs are identified by their GenBank accession numbers: Human aldose reductase (ALR, AAB88851), barley ALR1 (CAA88322), S. cerevisiae GCY1 (CAA65512), T. megachiliensis SNG-42 ER1 (BAD90687), T. megachiliensis SNG-42 ER2 (BAD90688), T. megachiliensis SNG-42 ER3 (BAD90689), and C. magnoliae JH110 ER (FJ550210). The tetra-amino acid motif, IPKS, conserved among NADPH-dependent reductases is indicated by a box. Gray-shaded amino acids are conserved in at least six of the seven AKRs shown. Black-shaded amino acids are conserved in all sequences.

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