Figure 1
From: Stepwise engineering of a Pichia pastoris D-amino acid oxidase whole cell catalyst
Industrial applications of Tv DAO. A: Chemo-enzymatic conversion of cephalosporin C to 7-aminocephalosporanic acid. Spontaneous decarboxylation of ketoadipyl-7-ACA (a mino c ephalosporanic a cid) is promoted by the H2O2 formed in the oxidase reaction of Tv DAO. B: Chemoenzymatic production of pure enantiomers of amino acids by amino acid oxidases in combination with imine reduction benefits from the additional presence of a catalase that destroys H2O2.