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Figure 6 | Microbial Cell Factories

Figure 6

From: Performance of the auxotrophic Saccharomyces cerevisiae BY4741 as host for the production of IL-1β in aerated fed-batch reactor: role of ACA supplementation, strain viability, and maintenance energy

Figure 6

Modeling of fed-batch reactor: cell density, residual glucose and product concentrations of S. cerevisiae BY4741 [PIR4-IL1 β ] (A) and S. cerevisiae BY4741 Δyca1 [PIR4-IL1 β ] (B). Simulation curves (continuous lines) and experimental data refer to viable biomass (empty rhomb), residual glucose (full square), and product concentration (full rhomb). (A), initial values (t = 0): XV0 = 3,08 g l-1, V0 = 1 l, F0 = 1.98*10-3 l h-1, G0 = 0, GR = 500 g l-1, P0 = 1.09*10-3 g l-1. (B), initial values (t = 0): XV0 = 3,37 g l-1, V0 = 1 l, F0 = 2.21*10-3 l h-1, G0 = 0, GR = 500 g l-1, P0 = 1.53*10-3 g l-1.

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Microbial Cell Factories

ISSN: 1475-2859

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