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Figure 2 | Microbial Cell Factories

Figure 2

From: Performance of the auxotrophic Saccharomyces cerevisiae BY4741 as host for the production of IL-1β in aerated fed-batch reactor: role of ACA supplementation, strain viability, and maintenance energy

Figure 2

Growth of S. cerevisiae BY4741 Δyca1 [PIR4-IL1 β ] in aerated fed-batch reactor, with either FC (full symbol) or FAC (empty symbol) solution in the feeding. 2A: time-course of biomass; in the insert the interpolation of the experimental data during the first 7 h of exponential feeding. 2B: time-course of residual glucose. Continuous and dashed lines represent the profiles of glucose fed to the reactor in the case of FC and FAC solutions, respectively. During fed-batch runs, the feeding was maintained for 28 h, being marked by an initial exponentially increasing feeding of 19 and 22 h followed by a constant feeding of 9 and 6 h for FC and FAC solutions, respectively. 2C: time-course of ethanol produced. 2D: time course of the product (IL-1β) secreted into the medium.

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