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Table 1 The uracil residue, nikkomycin Z production and biomass in culture medium of sanPDM with uracil supplementation

From: Selectively improving nikkomycin Z production by blocking the imidazolone biosynthetic pathway of nikkomycin X and uracil feeding in Streptomyces ansochromogenes

Uracil

(g/L)

Nikkomycin Z production

(mg/L)

Biomass

(g/L)

Uracil residue

(g/L)

0

300 ± 20

14.8 ± 2.2

ND

0.5

400 ± 15

13.4 ± 1.7

ND

1.0

480 ± 18

11.0 ± 2.2

ND

1.5

790 ± 23

9.5 ± 1.4

0.080 ± 0.020

2.0

800 ± 18

9.1 ± 1.0

0.484 ± 0.031

  1. ND, not detected in culture medium