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Table 2 Functional classification of metabolic reactions in a C. glutamicum genome-scale model.

From: Development and experimental verification of a genome-scale metabolic model for Corynebacterium glutamicum

Carbohydrate metabolism

45

Metabolism of complex carbohydrate

66

glycolysis/gluconeogenesis

18

arabinogalactan biosynthesis

2

TCA cycle

17

dTDP-rhamnose biosynthesis

5

pentose phosphate pathway

8

D-lactate metabolism

5

Entner-Doudoroff pathway

2

GDP-mannose metabolism

5

Energy metabolism

17

glycerol and glycerophosphodiester degradation

2

Lipid metabolism

32

mevalonate pathway

9

fatty acid biosynthesis

15

UDP-N-acetylgalactosamine biosynthesis

7

phospholipid biosynthesis

17

UDP-glucose conversion

3

Nucleotide metabolism

84

isopentenyl diphosphate biosynthesis

8

PRPP biosynthesis

1

glutathione redox reactions

4

purinebiosynthesis

29

myo-inositol biosynthesis

2

pyrimidine biosynthesis

23

Polysaccharide biosynthesis

1

nucleotide salvage pathway

31

peptidoglycan biosynthesis

13

Amino acid metabolism

103

Metabolism of complex lipid

13

glutamate biosynthesis

2

MAPc biosynthesis

1

glutamine biosynthesis

1

PIM2 biosynthesis

2

alanine biosynthesis

3

Mycolyl-ACP biosynthesis

1

valine biosynthesis

3

polyamine biosynthesis

7

aspartate biosynthesis

1

Corynomycolate biosynthesis

2

lysine biosynthesis

11

Metabolism of cofactors and vitamins

67

arginine biosynthesis

9

ATP maintenance

1

asparagine biosynthesis

2

coenzyme A biosynthesis

5

threonine biosynthesis

2

folate transformations

2

isoleucine biosynthesis

5

formylTHF biosynthesis

9

leucine biosynthesis

4

NAD biosynthesis

19

proline biosynthesis

5

O-antigen biosynthesis

1

serine biosynthesis

3

pantothenate biosynthesis

6

tyrosine biosynthesis

3

riboflavin and FMN and FAD biosynthesis

9

tryptophan biosynthesis

6

tetrahydrofolate biosynthesis

15

cysteine biosynthesis

2

Metabolism of other amino acids

9

phenylalanine biosynthesis

3

homoserine biosynthesis

1

glycine biosynthesis

1

chorismate biosynthesis

7

methionine biosynthesis

17

spermine biosynthesis

1

histidine biosynthesis

10

Metabolism of sugars

14

interconversion of arginine, ornithine and proline

10

trehalose biosynthesis

2

  

starch biosynthesis

12

  

Transport pathway

31

  

Biomass synthesis

1

  

Exchange pathway

34

  1. The reaction "Biomass synthesis" indicates the hypothetical reaction to synthesize biomass, which represents the requirement of precursors and coenzymes for the biomass formation.