Figure 1
From: Bioreactor mixing efficiency modulates the activity of a prpoS::GFP reporter gene in E. coli
scheme of the different reactor configuration used to study the influence of the extracellular heterogeneities on E. coli and expected substrate profiles. A : well mixed reactor with exponential feed control ; B : well mixed reactor with an ON/OFF feed control base on the DO level, leading to the appearance of oscillating extracellular conditions ; C : partitioned reactor with an ON/OFF feed control based on the DO level, the glucose being introduced at the level of the middle of the tubular part. The last configuration generate oscillating extracellular conditions for the microbial cells located in the stirred part of the reactor and the same cell can be stochastically exposed to strong concentration gradient in the tubular part.