Table 3 Peak areas of detected metabolites normalized to total peak area in BY4742 and the three deletion strains pat1Δ, dhh1Δ and lsm1Δ using GC/MS.

glycine

4.67E-05

1.10E-05

6.07E-05

1.12E-05

5.68E-05

4.58E-06

1.97E-04

2.26E-05

alanine

1.28E-04

2.68E-05

1.34E-04

3.07E-05

2.08E-04

3.27E-05

1.06E-03

1.71E-04

pyruvic acid

1.02E-05

5.52E-06

9.87E-06

2.62E-06

6.24E-06

8.64E-07

4.59E-06

6.12E-07

lactic acid

1.65E-05

1.72E-06

1.22E-05

2.44E-06

7.95E-06

1.47E-06

7.67E-06

2.35E-06

valine^E

4.73E-05

8.82E-06

6.02E-05

9.70E-06

4.91E-05

7.67E-06

1.80E-04

2.54E-05

u. m. #1

2.25E-05

5.10E-06

3.33E-05

6.92E-06

4.38E-05

1.92E-05

9.97E-06

2.39E-06

ethanolamine

8.47E-06

3.27E-06

6.76E-06

1.37E-06

1.14E-05

1.74E-06

2.11E-05

6.15E-06

glycerol

3.38E-04

5.49E-05

3.36E-04

2.36E-05

6.98E-04

6.75E-05

5.96E-04

1.01E-04

isoleucine/leucine^E

5.32E-06

2.21E-06

5.08E-06

1.04E-06

7.69E-06

5.53E-07

2.22E-05

3.13E-06

succinic acid

4.71E-06

1.74E-06

2.59E-06

1.08E-07

4.65E-06

2.64E-07

1.01E-05

1.09E-06

uracil

1.55E-05

3.05E-06

1.72E-05

3.08E-06

1.70E-05

5.16E-06

1.99E-05

2.05E-06

fumaric acid

4.56E-06

1.43E-06

6.06E-06

9.78E-07

8.08E-06

3.39E-07

1.78E-05

2.32E-06

serine

2.17E-05

5.77E-06

2.10E-05

2.57E-06

3.94E-05

3.32E-06

3.45E-05

6.43E-06

threonine^E

1.94E-05

4.14E-06

2.19E-05

2.94E-06

3.70E-05

3.35E-06

5.99E-05

5.37E-06

homoserine^N

9.32E-06

1.60E-06

9.77E-06

1.52E-06

1.71E-05

1.15E-06

2.50E-05

2.18E-06

malic acid

3.98E-06

9.76E-07

7.88E-06

9.28E-07

1.23E-05

8.03E-07

2.30E-05

3.55E-06

u. m. #2

2.41E-06

3.99E-07

2.50E-06

4.32E-07

3.69E-06

2.40E-07

4.60E-06

4.01E-07

Erythritol^N

2.13E-06

2.67E-07

1.75E-06

2.73E-07

n.d.¹

n.d.¹

n.d.¹

n.d.¹

aspartate

2.39E-05

3.44E-06

3.89E-05

3.18E-06

1.29E-04

1.20E-05

1.03E-04

1.43E-05

u. m. #6

7.99E-05

1.28E-05

7.55E-05

1.50E-05

4.56E-05

2.41E-06

4.82E-05

9.02E-06

cytosine

7.49E-06

1.03E-06

6.97E-06

1.21E-06

5.64E-06

1.90E-06

5.94E-06

1.05E-06

α-ketoglutaric acid

3.89E-07

1.84E-07

6.66E-07

9.73E-08

4.56E-07

8.42E-08

n.d.¹

n.d.¹

glutamate

6.97E-05

1.84E-05

1.45E-04

1.84E-05

1.33E-04

2.12E-05

8.20E-05

1.03E-05

phenylalanine^E

2.56E-06

6.33E-07

3.94E-06

4.11E-07

4.88E-06

7.75E-07

3.28E-06

4.78E-07

ribose

1.50E-06

4.90E-07

8.37E-07

1.52E-07

4.72E-07

7.98E-08

5.02E-07

1.66E-07

asparagine

1.79E-06

6.49E-07

2.34E-06

3.99E-07

3.91E-06

1.09E-06

2.37E-06

7.65E-07

2-aminoadipic acid

4.03E-06

1.22E-06

2.32E-06

3.72E-07

8.49E-07

1.57E-07

4.12E-06

4.93E-07

orotic acid

6.56E-05

2.11E-05

3.38E-05

2.74E-06

1.55E-05

2.70E-06

7.66E-05

1.05E-05

glycerol-1-phosphate

5.65E-07

1.05E-07

6.80E-07

4.76E-08

5.17E-07

1.10E-07

n.d.¹

n.d.¹

glutamine

1.86E-06

5.48E-07

4.54E-06

3.26E-06

1.46E-05

4.06E-06

4.19E-06

4.66E-06

N-acetyl-glutamic acid

5.62E-07

1.34E-07

1.63E-06

3.29E-07

5.72E-07

9.51E-08

n.d.¹

n.d.¹

u. m. #3

1.06E-05

7.65E-06

8.19E-06

1.98E-06

1.88E-06

1.75E-07

1.31E-05

1.94E-06

citric acid

9.43E-06

1.82E-06

1.47E-05

1.51E-06

4.79E-04

7.40E-05

1.28E-05

3.12E-06

ornithine

3.69E-06

1.17E-06

1.17E-05

1.40E-06

1.40E-05

2.94E-06

1.69E-06

3.42E-07

arginine

4.17E-06

1.10E-06

1.19E-05

1.88E-06

6.33E-06

1.33E-06

8.16E-07

4.37E-07

adenine

3.78E-06

8.22E-07

3.84E-06

9.41E-07

3.86E-06

1.24E-06

4.82E-06

7.76E-07

lysine^E

1.52E-04

4.67E-05

2.16E-04

1.11E-05

4.15E-04

3.30E-05

4.44E-04

5.42E-05

histidin^Ee

1.36E-05

1.63E-06

1.93E-05

8.38E-06

2.83E-05

3.25E-06

1.23E-05

8.86E-07

mannitol^N

4.96E-07

7.11E-08

1.03E-06

1.34E-07

6.30E-07

9.23E-08

9.67E-07

1.55E-07

tyrosine^E

8.22E-06

3.02E-06

2.14E-05

1.96E-06

1.93E-05

1.76E-06

1.72E-05

1.35E-06

u. m. #4

1.74E-06

3.53E-07

8.75E-07

1.18E-07

9.58E-07

1.96E-08

1.15E-06

2.03E-07

inositol

4.81E-05

9.72E-06

4.23E-05

3.34E-06

3.28E-05

1.83E-06

3.41E-05

3.38E-06

xylulose-5-phosphate

3.15E-06

1.36E-06

1.12E-06

1.55E-07

1.22E-06

2.81E-07

7.68E-07

6.53E-08

glucose-6-phosphate

6.96E-06

1.59E-06

5.92E-06

1.56E-06

2.11E-06

4.92E-07

1.54E-06

1.15E-06

u. m. #7

3.44E-06

5.64E-07

1.70E-06

6.00E-07

3.39E-06

1.12E-06

4.58E-06

5.05E-07

u. m. #5

2.56E-06

3.60E-07

2.73E-06

4.09E-07

1.69E-06

2.72E-07

1.75E-06

5.30E-07

trehalose^N

5.08E-06

9.10E-07

1.87E-04

5.06E-05

9.54E-05

2.70E-05

9.61E-04

2.13E-04