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Table 3 Growth and production kinetics of lysine producing C. glutamicum ATCC 13032 lysCfbr and lysCfbr Δpyk during batch cultivation on glucose.

From: Metabolic responses to pyruvate kinase deletion in lysine producing Corynebacterium glutamicum

Rates

lysCfbr

lysCfbr Δpyk

μ [1/h]

0.38 ± 0.00

0.35 ± 0.00

qGlc [mmol/g/h]

4.60 ± 0.08

4.50 ± 0.01

qLys [mmol/g/h]

0.38 ± 0.02

0.33 ± 0.00

  1. The specific growth rate was estimated as slope from the semi logarithmic plot of cell concentration versus time (Figures 1B and D). The specific glucose uptake rate (qGlc) was calculated from the specific growth rate (μ) and the biomass yield (Table 2). The specific lysine production rate (qLys) was calculated from qGlc and the lysine yield (Table 2). The values given here represent the mean value from three parallel cultivation experiments with corresponding deviations.
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Microbial Cell Factories

ISSN: 1475-2859

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