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Table 2 Growth and production stoichiometry of lysine producing C. glutamicum ATCC 13032 lysCfbr and lysCfbr Δpyk during batch cultivation on glucose.

From: Metabolic responses to pyruvate kinase deletion in lysine producing Corynebacterium glutamicum

Yield

lysCfbr

lysCfbr Δpyk

YX/Glc [g/mol]

82.1 ± 1.5

77.1 ± 0.2

YLys/Glc [mmol/mol]

82.0 ± 2.9

73.9 ± 0.9

YDHA/Glc [mmol/mol]

0.0 ± 0.0

20.8 ± 1.4

YGly/Glc [mmol/mol]

0.0 ± 0.0

6.2 ± 1.3

YTre/Glc [mmol/mol]

9.1 ± 0.4

2.9 ± 0.1

YLac/Glc [mmol/mol]

6.9 ± 0.6

7.5 ± 0.0

  1. The data given are biomass yield (YX/S), lysine yield (YLys/S) and yields on by-products glycerol (YGly/S), dihydroxyacetone (YDHA/S), trehalose (YTre/S) and lactate (YLac/S). The yields were determined as slope of the linear fit between biomass or product formation, respectively, and substrate consumption (compare Figures 1A and 1C). The values given here represent the mean value from three parallel cultivation experiments with corresponding deviations.