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Table 1 Examples of wild-type yeast whole-cell biocatalysts for the reduction of C=O bonds and comparison to S. cerevisiae, if provided.

From: Yeast cell factories for fine chemical and API production

Whole-Cell Biocatalyst

Substrate

Product

Performance: yield (ee)

Ref.

Candida parapsilosis IFO 1396

C.p.: 60% (98% S)

[61]

Candida arborea IAM 4147 Issatchenkia scutulata IFO 10070 Kluyveromyces lactis IFO 1267

 

C.a.: 37% (99% R) I.s.: 48% (99% R) K.l.: 99% (93% R)

 

Candida tropicalis PBR-2 MTCC 5158

C.t.: > 84% conv.a (> 99% S)

[62]

Geotrichum candidum CBS 233.76 with Amberlite XAD-1180

G.c.: 95% (> 98% S)

[60]

Rhodotorula mucillaginosa CBS 2378 Saccharomyces cerevisiae b

 

R.m.: 88% (> 99% R) S.c.: 95% (41% R)

 

Saccharomyces montanus CBS 6772 Saccharomyces cerevisiae (Type II from Sigma)

S.m.: eecis = 93% (1S,2S)

cis:trans = 96:4 S.c.: eecis = 90% (1S,2S)

cis:trans = 95:5

[57]

Saccharomyces cerevisiae (dried baker's yeast)

S.c.: – (94% R)

[58]

Saccharomyces cerevisiae

S.c.: 75% (> 99%); 96% de

[59]

Pichia mexicana CECTc 11015 Saccharomyces cerevisiae CECTc 1317

P.m.: 85–86% (95% R) S.c.: 48% (75% R)

[56]

Yarrowia lipolytica CECTc 1240 Saccharomyces cerevisiae (Type II, Sigma)

 

Y.l.: 87–88% (99% S) S.c.: 32% (83% S)

 

Kluyveromyces marxianus CBS 600 Saccharomyces cerevisiae GIV 2009d

K.m.: 2-PE: 26.5 g L-1 in org. phasee STY:f 0.33 g L-1 h-1 2-PEAc: 6.1 g L-1 in org. phasee STY:f 0.08 g L-1 h-1 S.c.: 2-PE: 24.0 g L-1 in org. phaseg after 166 h STY:f 0.14 g L-1 h-1

[63] [64]

  1. aconv. = conversion; bbaker's yeast from Distillerie Italiane, Eridania group; cSpanish type culture collection CECT, Valencia; dThe wild type strain S. cerevisiae Giv 2009 was from Givaudan Ltd. (Dübendorf, Switzerland); eorganic phase = Polypropylene glycol 1200 [63]; fSTY = space-time yield; calculated from t = 0 until t where the maximum product concentration was reached; gorganic phase = oleic acid [64].