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Figure 8 | Microbial Cell Factories

Figure 8

From: Folding and assembly of large macromolecular complexes monitored by hydrogen-deuterium exchange and mass spectrometry

Figure 8

Structural changes during HIV maturation [71, 115, 116]. (A) Progress of deuteration for the intact capsid protein (+28 charge state, 25 601 Da) in mature virus-like-particles (mVLP, red) and as disassembled monomer in solution (black). (B) Time-resolved isotopic envelopes for the peptic fragment encompassing residues 55–68 of the CA protein in immature (left) and mature (right) VLPs. The peaks marked by asterisk do not belong to the CA fragment envelopes. From [71] with permission.

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