Thioredoxin reductase is a key factor in the oxidative stress response of Lactobacillus plantarum WCFS1

Table 4 Crossover between genotype affected genes and hydrogen peroxide affected genes. Genes presented in this table are the common transcripts (16) between the two studied datasets: genotype and treatment. Further a summary of the regulation pattern for each of the depicted transcripts is given.

	FC¹					Transcript Behavior
Locus	genotype	treatment	Gene	Product	Main Functional Class	up	conflicting
lp_2716	1,6	0,7	ica3	glycosyltransferase (putative)	Cell envelope	•
lp_0728	0,6	1,7	groEL	GroEL chaperonin	Cellular processes		•
lp_2544	1,6	5,0	npr2	NADH peroxidase		•
lp_3020	1,6	0,7	tag2	DNA-3-methyladenine glycosylase I	DNA metabolism	•
lp_0789	1,7	1,8	gapB	glyceraldehyde 3-phosphate dehydrogenase	Energy metabolism	•
lp_1081	1,6	0,5		unknown	Hypothetical proteins	•
lp_1611	2,1	32,9		unknown		•
lp_1708	2,3	4,2		unknown		•
lp_1880	3,9	2,9		unknown		•
lp_2119	1,7	1,8	tuf	elongation factor Tu	Protein synthesis	•
lp_2721	1,5	3,1	purN	phosphoribosylglycinamide formyltransferase	Purines, pyrimidines, nucleosides and nucleotides	•
lp_2722	1,6	3,4	purM	phosphoribosylformylglycinamidine cyclo-ligase		•
lp_2729	1,7	1,8	purE	phosphoribosylaminoimidazole carboxylase, catalytic subunit		•
lp_0761	23,5	1,8	trxB1	thioredoxin reductase (NADPH)		•
lp_1087	1,8	0,6		cation transport protein	Transport and binding proteins	•
lp_2992	2,6	1,8	mntH2	manganese transport protein		•

ISSN: 1475-2859