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Table 3 Summary of significant affected genes (27) in the trxB1 over-expression strain, NZ7602, when compared to the wild type (pvalue < 0.01 & FC ≥ 1.5). Predicted gene names, function, fold change induction as well as main functional classes of the significant affected transcripts are displayed in columns. Main functional classes presented in bold are those classes found overrepresented in this study when compared to the total genome of L. plantarum.

From: Thioredoxin reductase is a key factor in the oxidative stress response of Lactobacillus plantarum WCFS1

Locus FC2 trx/wt Gene Product Main Functional Class (%)1
lp_0254 1,5 cysE serine O-acetyltransferase Amino acid biosynthesis (4%)
lp_3421 1,6   extracellular protein, gamma-D-glutamate-meso-diaminopimelate muropeptidase (putative) Cell envelope (7%)
lp_2716 1,6 ica3 glycosyltransferase (putative)  
lp_0728 0,6 groEL GroEL chaperonin Cellular processes (7%)
lp_2544 1,6 npr2 NADH peroxidase  
lp_3020 1,6 tag2 DNA-3-methyladenine glycosylase I DNA metabolism (4%)
lp_0789 1,7 gapB glyceraldehyde 3-phosphate dehydrogenase Energy metabolism (4%)
lp_1237 1,5   unknown Hypothetical proteins (19%)
lp_1081 1,6   unknown  
lp_1611 2,1   unknown  
lp_1708 2,3   unknown  
lp_1880 3,9   unknown  
lp_1023 1,8   type 4 prepilin-like proteins leader peptide processing enzyme (putative) Protein fate (4%)
lp_2119 1,7 tuf elongation factor Tu Protein synthesis(4%)
lp_2721 1,5 purN phosphoribosylglycinamide formyltransferase Purines, pyrimidines, nucleosides and nucleotides (15%)
lp_2722 1,6 purM phosphoribosylformylglycinamidine cyclo-ligase  
lp_2729 1,7 purE phosphoribosylaminoimidazole carboxylase, catalytic subunit  
lp_0761 23,5 trxB1 thioredoxin reductase (NADPH)  
lp_1230 1,6   transcription regulator Regulatory function (4%)
lp_3278 1,8   amino acid transport protein Transport and binding proteins (11%)
lp_1087 1,8   cation transport protein  
lp_2992 2,6 mntH2 manganese transport protein  
antilp_3469 1,6    
lp_RNA02 2,6    plasmids (15%)
lp_p2_01 3,1    
lp_p2_02 3,2    
lp_p3_05 1,5    
  1. 1values given in parenthesis correspond to the percentage of the total amount of genes (27) that belong to each depicted functional class.
  2. 2FC is fold change or 2M