Table 3 Studies on PMOs in bacteria.
From: Hitting bacteria at the heart of the central dogma: sequence-specific inhibition
PMO | Target | Test system | Reference |
|---|---|---|---|
20–21-mer PMOs, (KFF)3KC-PMOs and rTat-PMOs | 16S rRNA + acpP + lacI | E. coli BL21(DE3), SM101 and SM105 in solid + liquid culture | [214] |
7–20-mer PMO | acpP | E. coli SM101 and AS19 and HeLa liquid culture | [212] |
11-mer PMO | acpP | E. coli SM105 and AS19 in liquid culture + in mice | [215] |
10–11-mer PMOs with/without 4 different CPPs | acpP | E. coli K-12 and E2348/69 (EPEC) and S. enterica ser. Typh. liquid culture + EPEC in Caco-2 cells | [216] |
11-mer (RFF)3RXB-PMO | acpP | Mouse infected with E. coli K-12 | [217] |