Figure 7
From: Hitting bacteria at the heart of the central dogma: sequence-specific inhibition
10–23 DNA enzyme. Generalized representation of a 10–23 DNA enzyme-substrate complex. N: any nucleotide, N': nucleotide complementary to N, R: purine nucleotide, Y: pyrimidine nucleotide, R': purine complementary to Y, M: A or C, H: A, C or T and D: G, A, or T. The nucleotides likely to be directly involved in forming the catalytic site are highlighted in bold, and the arrow marks the cleavage site. Numbering is according to Zaborowska et al. [222].