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Table 1 Parameters for mean yield coefficient calculation at 10 and 300 L scale fermentation.

From: Set up and optimization of a fermentation protocol for the production of a human antibody fragment (Fab') express in E. coli. Pre-pilot and cGMP pilot scale studies

Fermentation Time OD600 DCW Substrate Fab Fab DCW Substrate YXS YPX YPS
scale (l) (h)   g.l-1 g.l-1 g.l-1 g.l-1.h g.l-1.h g.l-1.h g.g-1 g.g-1 g.g-1
    (X) (S) (P) (rP) (rX) (-rS)    
10 36 137 36.4 186 0.0642 0.00178 1.01 5.16 0.196 0.0018 0.00035
300            
3 8 10 2.9 15    0.36     
30 6 18 5.8 30    0.96     
300 37 136 36.2 190 0.0685 0.00185 0.98 5.13 0.190 0.0019 0.00036