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Table 2 LAB as vaccine vehicles

From: Live bacterial vaccines – a review and identification of potential hazards

Vaccine strain

Foreign insert

Model

Ref.

Lactococcus lactis

C. tetani TTFC

Mouse

[23,96]

 

TTFC+IL-2 or IL-6

Mouse

[97]

 

Human IL-10

Mouse

[39]

 

H. pylori ure B

Mouse

[98]

 

B. abortu s L7/L12

Mouse

[99]

 

S. pneumonie CPS

Mouse

[100]

 

Rotavirus vp7

Mouse

[101]

 

B-lactoglobulin

Mouse

[102]

 

HIV-1 gp120

Mouse

[103]

 

Malaria MSP-1

Mouse

[104]

 

SARS Nucleocapsid protein

In vitro

[105]

 

E. rhusiopathiae SpaA

Mouse

[106]

Lactobacillus plantarum

TTFC

Mouse

[107]

 

Allergen Der p1

Mouse

[36]

 

H. pylori (ureB)

Mouse

[108]

Streptococcus gordonii

Antibody

Rat

[34]

 

Hornet venom Ag5.2

Mouse

[109]

 

TTFC

Mouse

[110]

Lactobacillus casei

B. anthracis (protective Ag)

In vitro

[111]

 

SARS spike protein

Mouse

[112]

 

Human papillomavirus L1

In vitro

[113]

 

Coronavirus S glycoprotein

Mouse

[114]

 

S. pneumonie PsaA PspA

In vitro

[115]

Lactobacillus zeae

Antibody

Rat

[33]

Lactobacillus johnsonii

TTFC mimotope

Mouse

[116]