Table 3 Effect of the signal peptide and of the insertion of the LEISSTCDA synthetic propeptide on the secretion efficiency.

From: Protein secretion in Lactococcus lactis: an efficient way to increase the overall heterologous protein production

Protein	SE^a with SP_Nuc	SE with SP_Usp45	Reference
Nuc	60 %	>95 %	[25]
NucT	30 %	30 %	[25]
Protein	SE without LEISS	SE with LEISS	Reference
Nuc	60 %	80 %	[18]
NucT	30 %	90 %	[25]
L7/L12	35 %	50 %	[19]
AmyS^b	+	+++	[18]

^a: SE, secretion efficiency is the proportion of total protein which is present in the mature secreted form.
^b: SE was not determined by western blot and immuno revelation and thus could not be quantified but the activity plate assay demonstrated a clear secretion enhancement (+ to +++) with LEISS.

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