Figure 1From: Soluble expression of recombinant proteins in the cytoplasm of Escherichia coliDownstream applications employed to obtain soluble proteins from recombinant E. coli. As a common trait the in vivo strategies aims at lowering the metabolic burden associated with recombinant expression. Some of the mentioned strategies have therefore merely indirect influence on folding such as the use of tRNA complementation plasmids and stabilization of mRNA (see text and ref [1] for details).Back to article page