Figure 2
From: Novel nikkomycin analogues generated by mutasynthesis in Streptomyces ansochromogenes
HPLC analysis and bioassay of nikkomycin Px and Pz. HPLC analysis of fermentation broth from S. ansochromogenes 7100 and its derivatives (A) and bioassays of nikkomycin production against C. albicans (B) and A. longipes (C). WT: S. ansochromogenes 7100, ΔsanL: sanL disruption mutant, sanLc: sanL complementary strain, NA: nicotinic acid, HBA: 4-hydroxybenzoic acid, isoNA: isonicotinic acid, X: nikkomycin X, Z: nikkomycin Z, Px:nikkomycin Px, Pz: nikkomycin Pz.